Found 473 articles for: "atopic dermatitis"
Pilot Evaluation of a Novel Topical Formulation Containing High Level, Cholesterol-Dominant, Physiological Lipids for Specific Targeting of Skin Barrier Deficits in Aging Skin
December 2016 | Volume 15 | Issue 12 | Original Article | 1513 | Copyright © December 2016
BACKGROUND: Topical products with epidermal lipids in a ceramide-dominant ratio were originally developed to address atopic dermatitis. They have been used by extension to address the barrier deficits...
Read MoreManaging Occupational Irritant Contact Dermatitis Using a Two-Step Skincare Regimen Designed to Prevent Skin Damage and Support Skin Recovery
December 2016 | Volume 15 | Issue 12 | Original Article | 1504 | Copyright © December 2016
Occupational irritant contact dermatitis (ICD) affecting the hands is a common and difficult-to-manage condition. Occupations that necessitate contact with harsh chemicals, use of alcohol-based disinf...
Read MoreDevelopment of a Clinical Pathway for Atopic Dermatitis Patients: A Case-Based Approach
December 2016 | Volume 15 | Issue 12 | Original Article | 1485 | Copyright © December 2016
BACKGROUND: Atopic dermatitis (AD) is a common chronic skin condition, associated with significant patient morbidity. There are a myriad of excellent evidenced based guidelines to guide clinicians by ...
Read MoreEfficacy of a Hand Regimen in Skin Barrier Protection in Individuals With Occupational Irritant Contact Dermatitis
November 2016 | Volume 15 | Issue 11 | Supplement Individual Articles | 81 | Copyright © November 2016
BACKGROUND: Occupational irritant contact dermatitis (OICD) is a dif cult and hard to manage condition. It occurs more frequently in certain occupations where contact with harsh chemicals, use of alco...
Read MoreEfficacy of a Moisturizing Foam in Skin Barrier Regeneration and Itch Relief in Subjects Prone to Atopic Dermatitis
November 2016 | Volume 15 | Issue 11 | Supplement Individual Articles | 77 | Copyright © November 2016
INTRODUCTION: Atopic dermatitis (AD) is characterized by impaired epidermal barrier with increased transepidermal water loss (TEWL). Scratching further compromises skin integrity, contributing to a cy...
Read MoreEvidence-Based Skincare: The Importance of Offering Moisturization, Relief, and Protection in Common Skin Disorders
November 2016 | Volume 15 | Issue 11 | Supplement Individual Articles | 76 | Copyright © November 2016
Exogenous Factors in Skin Barrier Repair
November 2016 | Volume 15 | Issue 11 | Original Article | 1289 | Copyright © November 2016
The stratum corneum (SC) is the skin’s outermost layer and serves the primary function of acting as a shield to keep foreign matter out and to essential elements, such as moisture and water, in. Mai...
Read MorePipeline Previews
December 2015 | Volume 14 | Issue 12 | Features | 1490 | Copyright © December 2015
Pipeline Previews brings to you information on the newest drugs and medical products as they become available to the dermatologic community. This department may include additional information from the...
Read MoreCustomized Single-agent Therapy Management of Severe Inflammatory Acne: A Randomized, Double-blind, Parallel-group, Controlled Study of a New Treatment - Adapalene 0.3%-Benzoyl Peroxide 2.5% Gel
December 2015 | Volume 14 | Issue 12 | Original Article | 1427 | Copyright © December 2015
BACKGROUND: More effective therapies are needed in the specific treatment of severe inflammatory acne vulgaris.
OBJECTIVES: To demonstrate superior efficacy of adapalene 0.3%-benzoyl peroxide 2.5...
Read MoreSkin Microbiome in Patients With Psoriasis Before and After Balneotherapy at the Thermal Care Center of La Roche-Posay
December 2015 | Volume 14 | Issue 12 | Original Article | 1400 | Copyright © December 2015
BACKGROUND: Changes in the composition of microbial communities that colonize skin have been linked to several diseases including psoriasis. Nevertheless, the intra-individual dynamics and how these c...
Read MoreA Phase 2, Randomized, Controlled, Dose-Ranging Study Evaluating Crisaborole Topical Ointment, 0.5% and 2% in Adolescents With Mild to Moderate Atopic Dermatitis
December 2015 | Volume 14 | Issue 12 | Original Article | 1394 | Copyright © December 2015
BACKGROUND: Crisaborole is a novel, boron-based, small-molecule, topical phosphodiesterase-4 inhibitor in development for the treatment of patients with mild to moderate atopic dermatitis (AD).
M...
Read MoreRandomized, Double-Blind, Split-Face Study Evaluating Fractional Ablative Erbium:YAG Laser-Mediated Trans-Epidermal Delivery of Cosmetic Actives and a Novel Acoustic Pressure Wave Ultrasound Technology for the Treatment of Skin Aging, Melasma, and Acne Scars
November 2015 | Volume 14 | Issue 11 | Original Article | 1191 | Copyright © November 2015
BACKGROUND: Fractional laser resurfacing enhances trans-epidermal delivery (TED), however laser penetration depths >250- μm fail to substantively increase drug delivery.
AIM: Evaluate the s...
Read MoreIdentifying Signs of Tinea Pedis: A Key to Understanding Clinical Variables
October 2015 | Volume 14 | Issue 10 | Supplement Individual Articles | 42 | Copyright © October 2015
Tinea pedis is a frequently encountered dermatophytosis affecting the superficial skin of the feet, primarily of adults. The prevalence of tinea pedis has increased over the last several decades due t...
Read MoreOnychomycosis to Fungal Superinfection: Prevention Strategies and Considerations
October 2015 | Volume 14 | Issue 10 | Supplement Individual Articles | 32 | Copyright © October 2015
Onychomycosis is the most common fungal skin infection, and it is frequently seen in the setting of other concomitant fungal infections, the most common being tinea pedis. Infected nails become a rese...
Read MoreClinical Trial Review
October 2015 | Volume 14 | Issue 10 | Features | 1173 | Copyright © October 2015
Clinical Trial Review is a JDD department designed to provide physicians with information on drugs and devices undergoing clinical testing. It is our goal to inform the reader of the status of select ...
Read MoreCrisaborole Topical Ointment, 2% in Adults With Atopic Dermatitis: A Phase 2a, Vehicle-Controlled, Proof-of-Concept Study
October 2015 | Volume 14 | Issue 10 | Original Article | 1108 | Copyright © October 2015
BACKGROUND: A novel approach for treating atopic dermatitis (AD) is the inhibition of phosphodiesterase 4 (PDE4), an enzyme involved in the proinflammatory cascade. Crisaborole topical ointment, 2% is...
Read MoreThe Value of the Black Box Warning in Dermatology
July 2015 | Volume 14 | Issue 7 | Editorials | 660 | Copyright © July 2015
Boxed, or “black box” warnings are issued by the United States Food and Drug Administration (US FDA) as a means to label drugs associated with serious adverse events. However, there is no ...
Read MoreClinical Trial Report
June 2015 | Volume 14 | Issue 6 | Features | 643 | Copyright © June 2015
Clinical Trial Review is a JDD department designed to provide physicians with information on drugs and devices undergoing clinical testing. It is our goal to inform the reader of the status of select ...
Read MoreSevere Tacrolimus-Induced Granulomatous Rosacea Recalcitrant to Oral Tetracyclines
June 2015 | Volume 14 | Issue 6 | Case Reports | 628 | Copyright © June 2015
Topical tacrolimus has been observed to induce granulomatous rosacea (GR) in prior case reports and series. In most cases, patients recover fully after withdrawing tacrolimus and initiating doxycyclin...
Read MoreEvaluation of Seasonal Changes in Facial Skin With and Without Acne
June 2015 | Volume 14 | Issue 6 | Original Article | 593 | Copyright © June 2015
The objective of this study was to compare facial skin of adolescent males with (acne) and without acne (non-acne) over the course of 1 year. At study entry, presence of acne was determined by clinica...
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